Production and quality control of 82mRb and primary PET scans using its radiopharmaceutical for heart examinations [Persian]

Authors

  • Alireza Karimian Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
  • Amir Reza Jalilian Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
  • Mahshid Sabet Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
  • Mohammad Mirzaie Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
  • Mohsen Kiyomarsi Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
  • Nami Shadanpour Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
  • Pezhman Rowshanfarzad Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
  • Sedigheh Moradkhani Cyclotron and Nuclear Medicine Department, Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy Organization of Iran, Karaj, Iran
Abstract:

According to the importance of positron emitters in nuclear medicine, 82mRb was produced as a member of this group of radiopharmaceuticals. After being converted into an injectable form, enough information was provided for imaging with this radiopharmaceutical. 82mRb with high radioisotopic purity and half-life of 6.5 hours, in chloride form, can be considered as a suitable positron emitter for the assessment of myocardial function. As a result of the bombardment of 82Kr with 15.4 MeV protons, the activity of 35.04 mCi was finally achieved. The nuclear reaction efficiency was 6.37 mCi/μAh. The product had a high radiopharmaceutical purity, according to international standards.

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Journal title

volume 11  issue 2

pages  13- 19

publication date 2003-12-01

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